Automated description from the Alliance of Genome Resources (Release 3.0)
Exhibits actin filament binding activity and channel activity. Involved in several processes, including positive regulation of interleukin-1 secretion; response to ATP; and response to ischemia. Localizes to plasma membrane. Is expressed in male reproductive gland or organ; nervous system; sensory organ; and submandibular gland primordium. Orthologous to human PANX1 (pannexin 1).