Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables actin filament binding activity. Acts upstream of or within positive regulation of cytokine production; response to ATP; and response to ischemia. Located in plasma membrane. Is expressed in several structures, including central nervous system; foregut; limb bud; male reproductive gland or organ; and sensory organ. Human ortholog(s) of this gene implicated in depressive disorder. Orthologous to human PANX1 (pannexin 1).