Automated description from the Alliance of Genome Resources (Release 4.1.0)
Enables protein tag. Involved in defense response to other organism; positive regulation of bone mineralization; and positive regulation of erythrocyte differentiation. Acts upstream of or within ISG15-protein conjugation; modification-dependent protein catabolic process; and response to bacterium. Predicted to be located in extracellular region. Predicted to be part of cytosolic small ribosomal subunit. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in immunodeficiency 38. Orthologous to human ISG15 (ISG15 ubiquitin like modifier).