Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable co-receptor binding activity and transferrin receptor activity. Involved in regulation of postsynaptic membrane neurotransmitter receptor levels. Acts upstream of or within multicellular organismal-level iron ion homeostasis. Part of HFE-transferrin receptor complex. Is active in postsynapse. Is expressed in liver lobe; mesonephros; and urinary system. Used to study hemochromatosis type 3. Human ortholog(s) of this gene implicated in hemochromatosis and hemochromatosis type 3. Orthologous to human TFR2 (transferrin receptor 2).