Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable Rho-dependent protein serine/threonine kinase activity; aspartic-type endopeptidase inhibitor activity; and small GTPase binding activity. Involved in several processes, including podocyte cell migration; positive regulation of focal adhesion assembly; and response to angiotensin. Acts upstream of or within several processes, including apical constriction; bleb assembly; and negative regulation of motor neuron apoptotic process. Located in several cellular components, including cytoplasmic stress granule; lamellipodium; and ruffle. Is active in Schaffer collateral - CA1 synapse. Is expressed in several structures, including central nervous system; genitourinary system; gut; heart; and skeletal muscle. Orthologous to human ROCK1 (Rho associated coiled-coil containing protein kinase 1).