Excel File Text File *Disease is associated/modeled with this Gene or a homolog. More...
      Disease Term Human Homologs Mouse Homologs Mouse Models Homology Source
     amyotrophic lateral sclerosis type 1 SOD1* Sod1* 39 models HomoloGene and HGNC
amyotrophic lateral sclerosis type 10 TARDBP* Tardbp* 22 models HomoloGene and HGNC
amyotrophic lateral sclerosis type 6 FUS* Fus* 5 models HGNC
     amyotrophic lateral sclerosis PSMC4 Psmc4* 1 model HomoloGene and HGNC
amyotrophic lateral sclerosis EPG5 Epg5* 1 model HomoloGene and HGNC
amyotrophic lateral sclerosis ADARB1 Adarb1* 1 model HomoloGene and HGNC
amyotrophic lateral sclerosis ZNF106 Zfp106* 1 model HomoloGene and HGNC
amyotrophic lateral sclerosis type 1 VPS54 Vps54* 1 model HomoloGene and HGNC
amyotrophic lateral sclerosis type 1 VEGFA Vegfa* 1 model HomoloGene and HGNC
amyotrophic lateral sclerosis type 1 SOD2 Sod2* 1 model HomoloGene and HGNC
amyotrophic lateral sclerosis type 1 SNCG Sncg* 1 model HomoloGene and HGNC
     amyotrophic lateral sclerosis type 1 DCTN1* Dctn1 1 model HomoloGene and HGNC
amyotrophic lateral sclerosis type 1 NEFH* Nefh 4 models HomoloGene and HGNC
amyotrophic lateral sclerosis type 1 PRPH* Prph   HomoloGene and HGNC
amyotrophic lateral sclerosis type 11 FIG4* Fig4   HomoloGene and HGNC
amyotrophic lateral sclerosis type 12 OPTN* Optn   HomoloGene and HGNC
amyotrophic lateral sclerosis type 14 VCP* Vcp   HomoloGene and HGNC
amyotrophic lateral sclerosis type 15 UBQLN2* Ubqln2 2 models HomoloGene and HGNC
amyotrophic lateral sclerosis type 16 SIGMAR1* Sigmar1   HomoloGene and HGNC
amyotrophic lateral sclerosis type 17 CHMP2B* Chmp2b 2 models HomoloGene and HGNC
amyotrophic lateral sclerosis type 18 PFN1* Pfn1 2 models HomoloGene and HGNC
amyotrophic lateral sclerosis type 19 ERBB4* Erbb4   HomoloGene and HGNC
amyotrophic lateral sclerosis type 2 ALS2* Als2 3 "NOT" models HomoloGene and HGNC
amyotrophic lateral sclerosis type 20 HNRNPA1* Hnrnpa1   HGNC
amyotrophic lateral sclerosis type 21 MATR3* Matr3   HomoloGene and HGNC
amyotrophic lateral sclerosis type 22 TUBA4A* Tuba4a   HomoloGene and HGNC
amyotrophic lateral sclerosis type 23 ANXA11* Anxa11   HomoloGene and HGNC
amyotrophic lateral sclerosis type 4 SETX* Setx   HomoloGene and HGNC
amyotrophic lateral sclerosis type 5 SPG11* Spg11   HomoloGene and HGNC
amyotrophic lateral sclerosis type 8 VAPB* Vapb 1 model HomoloGene and HGNC
amyotrophic lateral sclerosis type 9 ANG* Ang   HomoloGene and HGNC
frontotemporal dementia and/or amyotrophic lateral sclerosis-1 C9orf72* C9orf72 1 model HomoloGene and HGNC
frontotemporal dementia and/or amyotrophic lateral sclerosis-2 CHCHD10* Chchd10   HomoloGene and HGNC
frontotemporal dementia and/or amyotrophic lateral sclerosis-3 SQSTM1* Sqstm1   HomoloGene and HGNC
frontotemporal dementia and/or amyotrophic lateral sclerosis-4 TBK1* Tbk1   HomoloGene and HGNC

 
Transgenes and other genome features developed in mice to model this disease.
     Disease Term Transgenes and Other Genome Features Mouse Models
  amyotrophic lateral sclerosis type 1 Tg(Thy1-SOD1*G93A)T3Hgrd 2 models
  amyotrophic lateral sclerosis type 1 Tg(Thy1-Sncg)HvP36Putt 1 model
  amyotrophic lateral sclerosis type 1 Tg(Thy1-DCTN1*G59S)M2Pcw 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*L126Z)#Deng 2 models
  amyotrophic lateral sclerosis type 1 Tg(SOD1*L126Z)45Dbo 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*H46R*H48Q)139Dbo 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*H46R*H48Q)58Dbo 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*H46R)LAra 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*H46R)IAra 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*H46R)#Maw 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*G127X)716Mrkl 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*G93A)dl1Gur 2 models
  amyotrophic lateral sclerosis type 1 Tg(Myl1-SOD1*G93A)#Amu 1 model
  amyotrophic lateral sclerosis type 1 Tg(NEFH)200Jpj 2 models
  amyotrophic lateral sclerosis type 1 Tg(NFH)120Jpj 2 models
  amyotrophic lateral sclerosis type 1 Tg(Prnp-Immt/SOD1*G93A)7Gmnf 1 model
  amyotrophic lateral sclerosis type 1 Tg(Prnp-SOD1*G37R,-PSEN1)110Dbo 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*)125Dbo 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*)D-14Dbo 2 models
  amyotrophic lateral sclerosis type 1 Tg(SOD1*)DF7Yaw 2 models
  amyotrophic lateral sclerosis type 1 Tg(SOD1*G37R)1Dwc 2 models
  amyotrophic lateral sclerosis type 1 Tg(SOD1*G37R)9Dpr 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*G37R)29Dpr 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*G37R)42Dpr 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*G37R)106Dpr 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*G85R)74Dwc 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*G85R)148Dwc 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*G85R)#Roos 2 models
  amyotrophic lateral sclerosis type 1 Tg(SOD1*G85R/EYFP)641Alho 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*G85R/EYFP)737Alho 1 model
  amyotrophic lateral sclerosis type 1 Tg(Sod1*G86R)M1Jwg 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*G93A)2Gur 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*G93A)1Gur 6 models
  amyotrophic lateral sclerosis type 10 Tg(Prnp-TARDBP*Q331K)103Dwc 1 model
  amyotrophic lateral sclerosis type 10 Tg(CAG-dsRed2/RNAi:Tardbp)6Zxu 1 model
  amyotrophic lateral sclerosis type 10 Tg(Prnp-TARDBP)3cPtrc 1 model
  amyotrophic lateral sclerosis type 10 Tg(Prnp-TARDBP)4Jlel 1 model
  amyotrophic lateral sclerosis type 10 Tg(Prnp-TARDBP*A315T)23Jlel 1 model
  amyotrophic lateral sclerosis type 10 Tg(Prnp-TARDBP*A315T)95Balo 1 model
  amyotrophic lateral sclerosis type 10 Tg(TARDBP)#Jpj 1 model
  amyotrophic lateral sclerosis type 10 Tg(TARDBP*A315T)#Jpj 1 model
  amyotrophic lateral sclerosis type 10 Tg(TARDBP*G348C)#Jpj 1 model
  amyotrophic lateral sclerosis type 10 Tg(tetO-TARDBP)12Vle 1 model
  amyotrophic lateral sclerosis type 10 Tg(tetO-TARDBP*)4Vle 2 models
  amyotrophic lateral sclerosis type 10 Tg(Thy1-TARDBP)4Singh 2 models
  amyotrophic lateral sclerosis type 10 Tg(Thy1-TARDBP)6Singh 1 model
  amyotrophic lateral sclerosis type 10 Tg(Thy1-TARDBP*)BOddo 1 model
  amyotrophic lateral sclerosis type 15 Tg(Thy1-UBQLN2*P506T)6Mont 1 model
  amyotrophic lateral sclerosis type 15 Tg(Thy1-UBQLN2*P497S)3Mont 1 model
  amyotrophic lateral sclerosis type 6 Tg(CAG-lacZ,-FUS,-EGFP)629Gyu 1 model
  amyotrophic lateral sclerosis type 6 Tg(Prnp-FUS*R521C)3313Ejh 1 model
  amyotrophic lateral sclerosis type 6 Tg(Thy1-FUS*)19Vlb 1 model
  amyotrophic lateral sclerosis type 6 Tg(CAG-lacZ,-FUS*R521G,-EGFP)682Gyu 1 model
  amyotrophic lateral sclerosis type 6 Tg(Prnp-FUS)WT3Cshw 1 model
  amyotrophic lateral sclerosis type 8 Tg(Thy1-VAPB*P56S,-EGFP)D3Cai 1 model
  frontotemporal dementia and/or amyotrophic lateral sclerosis-1 Tg(C9orf72)500Lpwr 1 model