| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
  | amyotrophic lateral sclerosis type 1 | SOD1* | Sod1* | 2 models | Alliance of Genome Resources | ||
| amyotrophic lateral sclerosis type 10 | TARDBP* | Tardbp* | 7 models | Alliance of Genome Resources | |||
| amyotrophic lateral sclerosis type 21 | MATR3* | Matr3* | 1 model | Alliance of Genome Resources | |||
| amyotrophic lateral sclerosis type 4 | SETX* | Setx* | 1 model | Alliance of Genome Resources | |||
| amyotrophic lateral sclerosis type 6 | FUS* | Fus* | 1 model | Alliance of Genome Resources | |||
| | amyotrophic lateral sclerosis | PSMC4 | Psmc4* | 1 model | Alliance of Genome Resources | ||
| amyotrophic lateral sclerosis | ADARB1 | Adarb1* | 1 model | Alliance of Genome Resources | |||
| amyotrophic lateral sclerosis | EPG5 | Epg5* | 1 model | Alliance of Genome Resources | |||
| amyotrophic lateral sclerosis | ZNF106 | Zfp106* | 1 model | Alliance of Genome Resources | |||
| amyotrophic lateral sclerosis | STMN2 | Stmn2* | 2 models | Alliance of Genome Resources | |||
| amyotrophic lateral sclerosis type 1 | VPS54 | Vps54* | 1 model | Alliance of Genome Resources | |||
| amyotrophic lateral sclerosis type 1 | VEGFA | Vegfa* | 1 model | Alliance of Genome Resources | |||
| amyotrophic lateral sclerosis type 1 | SOD2 | Sod2* | 1 model | Alliance of Genome Resources | |||
| | amyotrophic lateral sclerosis | NEFH* | Nefh | Alliance of Genome Resources | |||
| amyotrophic lateral sclerosis | NEFL* | Nefl | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis | OPTN* | Optn | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis | PON2* | Pon2 | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis | PON3* | Pon3 | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis | VDR* | Vdr | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis | VAPB* | Vapb | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis | UNC13A* | Unc13a | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis | UBQLN2* | Ubqln2 | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis | TXNRD1* | Txnrd1 | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis | TFAM* | Tfam | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis | TARDBP* | Tardbp | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis | SOD1* | Sod1 | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis | SLC11A2* | Slc11a2 | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis | PPARGC1A* | Ppargc1a | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis | ALS2* | Als2 | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis | ANG* | Ang, Ang2, Ang3, Ang4, Ang5, Ang6 | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis | AOX1* | Aox1 | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis | APOE* | Apoe | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis | CCS* | Ccs | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis | CHMP2B* | Chmp2b | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis | DPP6* | Dpp6 | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis | FUS* | Fus | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis | GOT1* | Got1 | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis | GRN* | Grn | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis | GSK3A* | Gsk3a | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis | GSK3B* | Gsk3b | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis | HMGB1* | Hmgb1 | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis | ITPR2* | Itpr2 | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis type 1 | DCTN1* | Dctn1 | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis type 1 | NEFH* | Nefh | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis type 1 | PRPH* | Prph | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis type 11 | FIG4* | Fig4 | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis type 12 | OPTN* | Optn | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis type 15 | UBQLN2* | Ubqln2 | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis type 16 | SIGMAR1* | Sigmar1 | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis type 18 | PFN1* | Pfn1 | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis type 19 | ERBB4* | Erbb4 | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis type 2 | ALS2* | Als2 | 3 "NOT" models | Alliance of Genome Resources | |||
| amyotrophic lateral sclerosis type 20 | HNRNPA1*, HNRNPA1L2 | Hnrnpa1, Hnrnpa1l2-ps2 | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis type 22 | TUBA4A* | Tuba4a | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis type 23 | ANXA11* | Anxa11 | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis type 24 | NEK1* | Nek1 | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis type 25 | KIF5A* | Kif5a | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis type 26 | TIA1* | Tia1 | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis type 28 | LRP12* | Lrp12 | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis type 5 | SPG11* | Spg11 | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis type 8 | VAPB* | Vapb | Alliance of Genome Resources | ||||
| amyotrophic lateral sclerosis type 9 | ANG* | Ang, Ang2, Ang3, Ang4, Ang5, Ang6 | Alliance of Genome Resources | ||||
| frontotemporal dementia and/or amyotrophic lateral sclerosis 1 | C9orf72* | C9orf72 | Alliance of Genome Resources | ||||
| frontotemporal dementia and/or amyotrophic lateral sclerosis 2 | CHCHD10* | Chchd10 | Alliance of Genome Resources | ||||
| frontotemporal dementia and/or amyotrophic lateral sclerosis 3 | SQSTM1* | Sqstm1 | Alliance of Genome Resources | ||||
| frontotemporal dementia and/or amyotrophic lateral sclerosis 4 | TBK1* | Tbk1 | Alliance of Genome Resources | ||||
| frontotemporal dementia and/or amyotrophic lateral sclerosis 6 | VCP* | Vcp | Alliance of Genome Resources | ||||
| frontotemporal dementia and/or amyotrophic lateral sclerosis 7 | CHMP2B* | Chmp2b | Alliance of Genome Resources | ||||
| juvenile amyotrophic lateral sclerosis type 27 | SPTLC1* | Sptlc1 | Alliance of Genome Resources | ||||
Excel File
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Transgenes and other genome features developed in mice to model this disease.
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| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| amyotrophic lateral sclerosis type 1 | Tg(Myl1-SOD1*G93A)#Amu | 1 model | |
| amyotrophic lateral sclerosis type 1 | Tg(NEFH)200Jpj | 2 models | |
| amyotrophic lateral sclerosis type 1 | Tg(NFH)120Jpj | 2 models | |
| amyotrophic lateral sclerosis type 1 | Tg(Prnp-Immt/SOD1*G93A)7Gmnf | 1 model | |
| amyotrophic lateral sclerosis type 1 | Tg(Prnp-SOD1*G37R,-PSEN1)110Dbo | 1 model | |
| amyotrophic lateral sclerosis type 1 | Tg(SOD1*)125Dbo | 1 model | |
| amyotrophic lateral sclerosis type 1 | Tg(SOD1*)D-14Dbo | 2 models | |
| amyotrophic lateral sclerosis type 1 | Tg(SOD1*)DF7Yaw | 2 models | |
| amyotrophic lateral sclerosis type 1 | Tg(SOD1*G37R)1Dwc | 2 models | |
| amyotrophic lateral sclerosis type 1 | Tg(SOD1*G37R)9Dpr | 1 model | |
| amyotrophic lateral sclerosis type 1 | Tg(SOD1*G37R)29Dpr | 1 model | |
| amyotrophic lateral sclerosis type 1 | Tg(SOD1*G37R)42Dpr | 1 model | |
| amyotrophic lateral sclerosis type 1 | Tg(SOD1*G37R)106Dpr | 1 model | |
| amyotrophic lateral sclerosis type 1 | Tg(SOD1*G85R)74Dwc | 1 model | |
| amyotrophic lateral sclerosis type 1 | Tg(SOD1*G85R)148Dwc | 1 model | |
| amyotrophic lateral sclerosis type 1 | Tg(SOD1*G85R)#Roos | 2 models | |
| amyotrophic lateral sclerosis type 1 | Tg(SOD1*G85R/EYFP)641Alho | 1 model | |
| amyotrophic lateral sclerosis type 1 | Tg(SOD1*G85R/EYFP)737Alho | 1 model | |
| amyotrophic lateral sclerosis type 1 | Tg(Sod1*G86R)M1Jwg | 1 model | |
| amyotrophic lateral sclerosis type 1 | Tg(SOD1*G93A)1Gur | 6 models | |
| amyotrophic lateral sclerosis type 1 | Tg(SOD1*G93A)2Gur | 1 model | |
| amyotrophic lateral sclerosis type 1 | Tg(SOD1*G93A)dl1Gur | 2 models | |
| amyotrophic lateral sclerosis type 1 | Tg(SOD1*G127X)716Mrkl | 1 model | |
| amyotrophic lateral sclerosis type 1 | Tg(SOD1*H46R)#Maw | 1 model | |
| amyotrophic lateral sclerosis type 1 | Tg(SOD1*H46R)IAra | 1 model | |
| amyotrophic lateral sclerosis type 1 | Tg(SOD1*H46R)LAra | 1 model | |
| amyotrophic lateral sclerosis type 1 | Tg(SOD1*H46R*H48Q)58Dbo | 1 model | |
| amyotrophic lateral sclerosis type 1 | Tg(SOD1*H46R*H48Q)139Dbo | 1 model | |
| amyotrophic lateral sclerosis type 1 | Tg(SOD1*L126Z)45Dbo | 1 model | |
| amyotrophic lateral sclerosis type 1 | Tg(SOD1*L126Z)#Deng | 2 models | |
| amyotrophic lateral sclerosis type 1 | Tg(Thy1-DCTN1*G59S)M2Pcw | 1 model | |
| amyotrophic lateral sclerosis type 1 | Tg(Thy1-Sncg)HvP36Putt | 1 model | |
| amyotrophic lateral sclerosis type 1 | Tg(Thy1-SOD1*G93A)T3Hgrd | 2 models | |
| amyotrophic lateral sclerosis type 10 | Tg(Prnp-TARDBP)4Jlel | 1 model | |
| amyotrophic lateral sclerosis type 10 | Tg(Prnp-TARDBP)3cPtrc | 1 model | |
| amyotrophic lateral sclerosis type 10 | Tg(Thy1-TARDBP*)BOddo | 1 model | |
| amyotrophic lateral sclerosis type 10 | Tg(Thy1-TARDBP)6Singh | 1 model | |
| amyotrophic lateral sclerosis type 10 | Tg(Thy1-TARDBP)4Singh | 2 models | |
| amyotrophic lateral sclerosis type 10 | Tg(tetO-TARDBP*A315T)13Lmit | 1 model | |
| amyotrophic lateral sclerosis type 10 | Tg(tetO-TARDBP*)4Vle | 2 models | |
| amyotrophic lateral sclerosis type 10 | Tg(CAG-dsRed2/RNAi:Tardbp)6Zxu | 1 model | |
| amyotrophic lateral sclerosis type 10 | Tg(tetO-TARDBP)12Vle | 1 model | |
| amyotrophic lateral sclerosis type 10 | Tg(Prnp-TARDBP*A315T)95Balo | 1 model | |
| amyotrophic lateral sclerosis type 10 | Tg(Prnp-TARDBP*A315T)23Jlel | 1 model | |
| amyotrophic lateral sclerosis type 10 | Tg(TARDBP*G348C)#Jpj | 1 model | |
| amyotrophic lateral sclerosis type 10 | Tg(TARDBP*A315T)#Jpj | 1 model | |
| amyotrophic lateral sclerosis type 10 | Tg(TARDBP)#Jpj | 1 model | |
| amyotrophic lateral sclerosis type 10 | Tg(Prnp-TARDBP*Q331K)103Dwc | 1 model | |
| amyotrophic lateral sclerosis type 15 | Tg(Thy1-UBQLN2*P497S)3Mont | 1 model | |
| amyotrophic lateral sclerosis type 15 | Tg(Thy1-UBQLN2*P506T)6Mont | 1 model | |
| amyotrophic lateral sclerosis type 4 | Tg(Prnp-SETX*R2136H)1920Als | 1 model | |
| amyotrophic lateral sclerosis type 6 | Tg(CAG-lacZ,-FUS*R521G,-EGFP)682Gyu | 1 model | |
| amyotrophic lateral sclerosis type 6 | Tg(CAG-lacZ,-FUS,-EGFP)629Gyu | 1 model | |
| amyotrophic lateral sclerosis type 6 | Tg(Prnp-FUS)WT3Cshw | 1 model | |
| amyotrophic lateral sclerosis type 6 | Tg(Prnp-FUS*R521C)3313Ejh | 1 model | |
| amyotrophic lateral sclerosis type 6 | Tg(Thy1-FUS*)1Dit | 1 model | |
| amyotrophic lateral sclerosis type 6 | Tg(Thy1-FUS*)19Vlb | 1 model | |
| amyotrophic lateral sclerosis type 8 | Tg(Thy1-VAPB*P56S,-EGFP)D3Cai | 1 model | |
| frontotemporal dementia and/or amyotrophic lateral sclerosis 1 | Tg(C9orf72)500Lpwr | 1 model | |