primary ovarian insufficiency 16 (DOID:0080873)
Alliance: disease page
Alt IDs: OMIM:618723
Definition: A primary ovarian insufficiency that is characterized by onset of amenorrhea early in the fourth decade of life, accompanied by elevated follicle-stimulating hormone levels and low estradiol levels and that has_material_basis_in heterozygous mutation in the BNC1 gene on chromosome 15q25.