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Gene Expression Data
Assay Details
Assay
Reference: J:254842 Fujita J, et al., Ronin Governs Early Heart Development by Controlling Core Gene Expression Programs. Cell Rep. 2017 Nov 7;21(6):1562-1573
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6714277
Gene symbol: Rps6
Gene name: ribosomal protein S6
Antibody: phospho-RPS6 (ser235/236) antibody (#2211)
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen S9B Control: embryonic day 11.5; Thap11tm1Tpz/Thap11+, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant. Double labeled: red - Rps6; green - Actn2 (assay MGI:6714260).
Structure Level Pattern Image Note
TS19: cardiac muscle tissue Present S9B Control p-RPS6 , S9B Control Merge Expression was in cardiomyocytes.

Specimen S9B Ronin KO: embryonic day 11.5; Thap11tm1Tpz/Thap11tm1Tpz, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant. Double labeled: red - Rps6; green - Actn2 (assay MGI:6714260).
Structure Level Pattern Image Note
TS19: cardiac muscle tissue Weak S9B Ronin KO Merge , S9B Ronin KO p-RPS6 Knockout embryos showed little phosphorylated Rps6 in cardiomyocytes. Actn2 expression level remained similar to control.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/16/2021
MGI 6.17
The Jackson Laboratory