Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cdkal1tm1.2Tomik
Name:	CDK5 regulatory subunit associated protein 1-like 1; targeted mutation 1.2, Kazuhito Tomizawa
MGI ID:	MGI:5301443
Gene:	Cdkal1  Location: Chr13:29375729-30039657 bp, - strand  Genetic Position: Chr13, 12.93 cM, cytoband A3.3
Alliance:	Cdkal1tm1.2Tomik page

Germline Transmission:	Earliest citation of germline transmission: J:178248
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Cre-mediated recombination of Cdkal1tm1.1Tomik removed exon 5. (J:178248)

Generation of the Cdkal1tm1.1Tomik and Cdkal1tm1.2Tomik alleles

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdkal1 Mutation:	59 strains or lines available

Original:	J:178248 Wei FY, et al., Deficit of tRNA(Lys) modification by Cdkal1 causes the development of type 2 diabetes in mice. J Clin Invest. 2011 Sep 1;121(9):3598-608
All:	1 reference(s)