Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Sox5tm2Vlf
Name:	SRY (sex determining region Y)-box 5; targeted mutation 2, Veronique Lefebvre
MGI ID:	MGI:3799354
Synonyms:	Sox5fl+
Gene:	Sox5  Location: Chr6:143774151-144727703 bp, - strand  Genetic Position: Chr6, 76.14 cM
Alliance:	Sox5tm2Vlf page

Germline Transmission:	Earliest citation of germline transmission: J:137217
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon CE5 and an frt-flanked neo cassette with a 3' loxP site was inserted downstream of exon CE5. Germ line, flp-mediated recombination was use remove the neo cassette leaving exon 5 floxed. (J:137217)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sox5 Mutation:	44 strains or lines available

Original:	J:137217 Dy P, et al., Generation of mice harboring a Sox5 conditional null allele. Genesis. 2008 Jun;46(6):294-9
All:	9 reference(s)