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Mta2tm1Yzha
Targeted Allele Detail
Summary
Symbol: Mta2tm1Yzha
Name: metastasis-associated gene family, member 2; targeted mutation 1, Yi Zhang
MGI ID: MGI:3798814
Synonyms: Mta22lox
Gene: Mta2  Location: Chr19:8919239-8929659 bp, + strand  Genetic Position: Chr19, 6.04 cM, cytoband B
Alliance: Mta2tm1Yzha page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:137101
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA neo cassette with a 5' loxP site was inserted into intron 3 and an additional loxP site was inserted into exon 11. (J:137101)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mta2 Mutation:  36 strains or lines available
References
Original:  J:137101 Lu X, et al., Inactivation of NuRD component Mta2 causes abnormal T cell activation and lupus-like autoimmune disease in mice. J Biol Chem. 2008 May 16;283(20):13825-33
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory