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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mta2tm1Yzha
targeted mutation 1, Yi Zhang
MGI:3798814
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Mta2tm1Yzha/Mta2tm1Yzha
Tg(Lck-cre)#Zhu/0 		involves: 129S4/SvJae * C57BL/6 * SJL MGI:3803012


Genotype
MGI:3803012
cn1
Allelic
Composition		 Mta2tm1Yzha/Mta2tm1Yzha
Tg(Lck-cre)#Zhu/0
Genetic
Background		 involves: 129S4/SvJae * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mta2tm1Yzha mutation (0 available); any Mta2 mutation (32 available)
Tg(Lck-cre)#Zhu mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:137101 )
N
• despite an increase in T cell proliferation, mice fail to exhibit other auto-immune phenotypes observed in Mta2tm1.1Yzha homozygotes
increased T cell proliferation ( J:137101 )
• upon stimulation

hematopoietic system
increased T cell proliferation ( J:137101 )
• upon stimulation

cellular
increased T cell proliferation ( J:137101 )
• upon stimulation




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory