Analysis Tools
reproductive system
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• sperm tails are almost absent in stage II-III and stage VII-VIII seminiferous tubules
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• sperm tail length ranges from ~20 to 120 um, significantly shorter than in controls
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• spermatoza are nearly absent in the epididymis
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• round heads
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• abnormal morphology is seen starting at step 9
• in step 9 spermatids, the centrosome fails to correctly dock onto the nuclear envelope
• acetylated tubulin accumulates around the round spermatid but not in the correct position
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• step 13-16 elongated spermatids are almost absent
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• abnormally long manchette
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• signs of apoptosis are seen in seminiferous tubules
• increase in the percentage of seminiferous tubules carrying apoptotic spermatids
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• mature spermatozoa show no motility
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small testis
(
J:367324
)
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• in stage VII seminiferous tubules a few of the step 16 spermatids are intermixed with step 7 spermatids and their tails are not visible in sections unlike in controls
• step 13-16 elongated spermatids are almost absent
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• when mated to wild-type females no pups were produced despite copulation occurring
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cellular
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• sperm tails are almost absent in stage II-III and stage VII-VIII seminiferous tubules
|
|
|
• sperm tail length ranges from ~20 to 120 um, significantly shorter than in controls
|
|
|
• spermatoza are nearly absent in the epididymis
|
|
|
• round heads
|
|
|
• abnormal morphology is seen starting at step 9
• in step 9 spermatids, the centrosome fails to correctly dock onto the nuclear envelope
• acetylated tubulin accumulates around the round spermatid but not in the correct position
|
|
|
• step 13-16 elongated spermatids are almost absent
|
|
|
• abnormally long manchette
|
|
|
• signs of apoptosis are seen in seminiferous tubules
• increase in the percentage of seminiferous tubules carrying apoptotic spermatids
|
|
|
• mature spermatozoa show no motility
|
endocrine/exocrine glands
small testis
(
J:367324
)
|
|
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