Phenotypes for Gt(ROSA)26Sor Pgbd5 MGI:7616743 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Gt(ROSA)26Sor^{tm1(Smo/EYFP)Amc}/Gt(ROSA)26Sor^{tm2(EGFP/cre)Alj} Pgbd5^tm1.1Aken/Pgbd5^tm1.1Aken
Genetic Background	involves: 129 * C57BL/6J * C57BL/6NTac * SW

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor^{tm1(Smo/EYFP)Amc} mutation (1 available); any Gt(ROSA)26Sor mutation (1062 available)
Gt(ROSA)26Sor^{tm2(EGFP/cre)Alj} mutation (2 available); any Gt(ROSA)26Sor mutation (1062 available)
Pgbd5^tm1.1Aken mutation (1 available); any Pgbd5 mutation (35 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

increased medulloblastoma incidence ( J:346387 )

• develop tumors with a similar latency to mice with one wild-type Pgbd5 allele, but most tumors retain an unrecombined floxed Pgbd5 allele

nervous system

increased medulloblastoma incidence ( J:346387 )

• develop tumors with a similar latency to mice with one wild-type Pgbd5 allele, but most tumors retain an unrecombined floxed Pgbd5 allele

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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