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Phenotypes Associated with This Genotype
Genotype
MGI:7545282
Allelic
Composition		 Pdgfratm8Sor/Pdgfratm8Sor
Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(cre/ERT)Nat mutation (3 available); any Gt(ROSA)26Sor mutation (1062 available)
Pdgfratm8Sor mutation (1 available); any Pdgfra mutation (88 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal dorsal mesocardium morphology ( J:157946 )
• inferior fusion defects resulting in notching of the inferior portion
total anomalous pulmonary venous connection ( J:157946 )
• rare but consistent phenotype

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory