Phenotypes Associated with This Genotype

Genotype
MGI:7415084

• Allelic Composition: Sox21^em1(IMPC)Mbp/Sox21^em1(IMPC)Mbp
• Genetic Background: C57BL/6NCrl-Sox21^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Sox21

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

decreased total body fat amount ( J:211773 )

♂

IMPC - UCD

behavior/neurological

decreased exploration in new environment ( J:211773 )

♀

IMPC - UCD

decreased startle reflex ( J:211773 )

♂

IMPC - UCD

decreased grip strength ( J:211773 )

IMPC - UCD

decreased locomotor activity ( J:211773 )

♀

IMPC - UCD

hyperactivity ( J:211773 )

♀

IMPC - UCD

growth/size/body

increased lean body mass ( J:211773 )

♂

IMPC - UCD

decreased body length ( J:211773 )

IMPC - UCD

enlarged kidney ( J:211773 )

♂

IMPC - UCD

hematopoietic system

increased mean corpuscular volume ( J:211773 )

♂

IMPC - UCD

increased neutrophil cell number ( J:211773 )

♀

IMPC - UCD

decreased lymphocyte cell number ( J:211773 )

IMPC - UCD

increased monocyte cell number ( J:211773 )

♂

IMPC - UCD

homeostasis/metabolism

decreased circulating cholesterol level ( J:211773 )

♂

IMPC - UCD

decreased circulating HDL cholesterol level ( J:211773 )

♂

IMPC - UCD

decreased circulating serum albumin level ( J:211773 )

♂

IMPC - UCD

immune system

increased neutrophil cell number ( J:211773 )

♀

IMPC - UCD

decreased lymphocyte cell number ( J:211773 )

IMPC - UCD

increased monocyte cell number ( J:211773 )

♂

IMPC - UCD

abnormal lymph node morphology ( J:211773 )

IMPC - UCD

enlarged lymph nodes ( J:211773 )

IMPC - UCD

integument

abnormal coat/ hair morphology ( J:211773 )

IMPC - UCD

abnormal skin morphology ( J:211773 )

IMPC - UCD

liver/biliary system

abnormal liver morphology ( J:211773 )

♀

IMPC - UCD

small liver ( J:211773 )

♀

IMPC - UCD

nervous system

abnormal brain morphology ( J:211773 )

IMPC - UCD

hydrocephaly ( J:211773 )

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

♂

IMPC - UCD

enlarged kidney ( J:211773 )

♂

IMPC - UCD

skeleton

decreased bone mineral content ( J:211773 )

♂

IMPC - UCD

decreased bone mineral density ( J:211773 )

♂

IMPC - UCD