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Phenotypes Associated with This Genotype
Genotype
MGI:7336693
Allelic
Composition		 Alx1em1Jian/Alx1em1Jian
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * C57BL/6N * CBA/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Alx1em1Jian mutation (0 available); any Alx1 mutation (22 available)
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo mutation (10 available); any Gt(ROSA)26Sor mutation (1062 available)
H2az2Tg(Wnt1-cre)11Rth mutation (2 available); any H2az2 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
embryo phenotype ( J:320497 )
N
• at E9.5 and E10.5, normal patterns of GFP-labeled cranial neural crest cells (CNCCs) are seen in the frontonasal and periocular regions as well as in the branchial arches
• at E10.5, the contribution of GFP-labeled CNCCs in the nasal, maxillary, and mandibular processes is similar to that in control embryos

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory