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Phenotypes Associated with This Genotype
Genotype
MGI:7310427
Allelic
Composition		 Rpap3tm1c(KOMP)Wtsi/Rpap3tm1c(KOMP)Wtsi
Tg(Vil1-cre/ERT2)23Syr/0
Trp53tm1Tyj/Trp53tm1Tyj
Genetic
Background		 involves: 129S2/SvPas * C57BL/6N * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rpap3tm1c(KOMP)Wtsi mutation (0 available); any Rpap3 mutation (36 available)
Tg(Vil1-cre/ERT2)23Syr mutation (1 available)
Trp53tm1Tyj mutation (12 available); any Trp53 mutation (236 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
abnormal small intestine morphology ( J:314346 )
• tamoxifen-treated mice exhibit a delay in epithelium shrinkage compared mice with at least one copy of wild-type Trp53
decreased small intestine length ( J:314346 )
• in tamoxifen-treated mice after 7 days

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory