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Phenotypes Associated with This Genotype
Genotype
MGI:7266839
Allelic
Composition		 Adgrg6tm1Arte/Adgrg6tm1Arte
Tg(Col2a1/Acan-rtTA,tetO-cre)#Vlf/0
Genetic
Background		 involves: 129S5/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adgrg6tm1Arte mutation (0 available); any Adgrg6 mutation (63 available)
Tg(Col2a1/Acan-rtTA,tetO-cre)#Vlf mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
abnormal intervertebral disk morphology ( J:313834 )
• altered extracellular matrix component expression and endplate-oriented disk herniations at 8 months of age
scoliosis ( J:313834 )
• embryonic induction of recombinase induction resulted in scoliosis in 25% and 16.7% of mice with Cobb angles of 11 to 43 degrees at P20 and P180, respectively

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory