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Phenotypes Associated with This Genotype
Genotype
MGI:6387024
Allelic
Composition		 Nfkb2Lym1/Nfkb2+
Otub1tm1c(EUCOMM)Hmgu/Otub1tm1c(EUCOMM)Hmgu
Cd19tm1(cre)Cgn/Cd19+
Genetic
Background		 involves: 129P2/OlaHsd * BALB/c * C57BL/6 * C57BL/6N
Cell Lines HEPD0539_8_A05
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd19tm1(cre)Cgn mutation (12 available); any Cd19 mutation (57 available)
Nfkb2Lym1 mutation (2 available); any Nfkb2 mutation (52 available)
Otub1tm1c(EUCOMM)Hmgu mutation (0 available); any Otub1 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:280549 )
N
• mice show rescue of the defect in peripheral B cells, with an increase in total peripheral B cells, mature B cells, and follicular and MZ B cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory