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Phenotypes Associated with This Genotype
Genotype
MGI:6377667
Allelic
Composition		 Cd9tm1c(EUCOMM)Hmgu/Cd9+
Krastm4Tyj/Kras+
Tg(Pdx1-cre)6Tuv/0
Trp53tm1Brn/Trp53+
Genetic
Background		 involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6N * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd9tm1c(EUCOMM)Hmgu mutation (0 available); any Cd9 mutation (101 available)
Krastm4Tyj mutation (12 available); any Kras mutation (88 available)
Tg(Pdx1-cre)6Tuv mutation (4 available)
Trp53tm1Brn mutation (21 available); any Trp53 mutation (249 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased glutamic acid level ( J:280854 )
• reduced glutamate uptake and intracellular levels in organoids derived from tumor initiating cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory