Phenotypes for anx Tg(Tyro3*-Gfp)1Sapc Tyro3 MGI:6287394 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	anx/anx Tg(Tyro3*-Gfp)1Sapc/? Tyro3^m1/Tyro3^m1
Genetic Background	involves: C3HeB/FeJLe * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
anx mutation (1 available); any anx mutation (1 available)
Tg(Tyro3*-Gfp)1Sapc mutation (0 available)
Tyro3^m1 mutation (4 available); any Tyro3 mutation (40 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

tremors ( J:241666 )

abnormal head movements ( J:241666 )

mortality/aging

premature death ( J:241666 )

growth/size/body

cachexia ( J:241666 )

• unlike wildtype Tyro3, transgenic expression of this R7W point mutant transgene fails to resuce the anx homozygous phenotype, specifically cachexia, death by 21 days of age, and behavioral phenotypes such as head tossing and tremors

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