Phenotypes Associated with This Genotype

Genotype
MGI:6263703

• Allelic Composition: Tmem116^{tm1b(EUCOMM)Hmgu}/Tmem116^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Tmem116^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0743_7_C04

Data Sources

IMPC Data for Tmem116

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal startle reflex ( J:211773 )

♂

IMPC - HMGU

increased grip strength ( J:211773 )

♂

IMPC - HMGU

growth/size/body

decreased body weight ( J:211773 )

♂

IMPC - HMGU

enlarged spleen ( J:211773 )

♀

IMPC - HMGU

hematopoietic system

enlarged spleen ( J:211773 )

♀

IMPC - HMGU

homeostasis/metabolism

decreased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - HMGU

decreased circulating total protein level ( J:211773 )

IMPC - HMGU

improved glucose tolerance ( J:211773 )

♂

IMPC - HMGU

immune system

enlarged spleen ( J:211773 )

♀

IMPC - HMGU

enlarged lymph nodes ( J:211773 )

♀

IMPC - HMGU

respiratory system

abnormal lung morphology ( J:211773 )

♀

IMPC - HMGU

vision/eye

abnormal lens morphology ( J:211773 )

♀

IMPC - HMGU