Phenotypes for Cxcr4 Lyz2 MGI:6116482 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Cxcr4^tm2Yzo/Cxcr4^tm2Yzo Lyz2^tm1(cre)Ifo/Lyz2⁺
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cxcr4^tm2Yzo mutation (1 available); any Cxcr4 mutation (50 available)
Lyz2^tm1(cre)Ifo mutation (16 available); any Lyz2 mutation (40 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

increased neutrophil cell number ( J:217569 )

increased lymphocyte cell number ( J:217569 )

increased monocyte cell number ( J:217569 )

adipose tissue

adipose tissue phenotype ( J:217569 )

N	• mice fed standard chow or a high-fat diet exhibit normal adiposity and lymphocyte numbers in white adipose tissue

growth/size/body

growth/size/body region phenotype ( J:217569 )

N	• mice fed standard chow or a high-fat diet exhibit normal weight gain

hematopoietic system

increased neutrophil cell number ( J:217569 )

increased lymphocyte cell number ( J:217569 )

increased monocyte cell number ( J:217569 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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