Phenotypes for Cd19 Gt(ROSA)26Sor Malt1 MGI:5908455 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Cd19^tm1(cre)Cgn/Cd19⁺ Gt(ROSA)26Sor^{tm2(CARD11*L225LI)Jrld}/Gt(ROSA)26Sor⁺ Malt1^tm1Mak/Malt1^tm1Mak
Genetic Background	involves: 129P2/OlaHsd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd19^tm1(cre)Cgn mutation (11 available); any Cd19 mutation (56 available)
Gt(ROSA)26Sor^{tm2(CARD11*L225LI)Jrld} mutation (0 available); any Gt(ROSA)26Sor mutation (942 available)
Malt1^tm1Mak mutation (1 available); any Malt1 mutation (33 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

mortality/aging ( J:228288 )

N	• absence of Malt1 expression rescues the early lethality seen in mutant mice wild-type for Malt1

immune system

immune system phenotype ( J:228288 )

N	• absence of Malt1 expression rescues the pathological B-cell activation, differentiation, and malignant proliferation seen in mutant mice wild-type for Malt1

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23