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Phenotypes Associated with This Genotype
Genotype
MGI:5903300
Allelic
Composition		 Cd83tm1.1Lnjt/Cd83tm1.1Lnjt
Marchf1tm1.1Sish/Marchf1tm1.1Sish
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd83tm1.1Lnjt mutation (0 available); any Cd83 mutation (16 available)
Marchf1tm1.1Sish mutation (1 available); any Marchf1 mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased CD4-positive, alpha-beta T cell number ( J:236611 )
• in the thymus as in Cd83tm1.1Lnjt homozygotes

hematopoietic system
decreased CD4-positive, alpha-beta T cell number ( J:236611 )
• in the thymus as in Cd83tm1.1Lnjt homozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory