Phenotypes Associated with This Genotype

Genotype
MGI:5756940

• Allelic Composition: Cyp27b1^{tm1b(EUCOMM)Hmgu}/Cyp27b1^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Cyp27b1^{tm1b(EUCOMM)Hmgu}/Tcp
• Cell Lines: HEPD0716_5_F01

Data Sources

IMPC Data for Cyp27b1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

decreased total body fat amount ( J:211773 )

♂

IMPC - TCP

behavior/neurological

decreased exploration in new environment ( J:211773 )

♀

IMPC - TCP

decreased grip strength ( J:211773 )

IMPC - TCP

decreased locomotor activity ( J:211773 )

IMPC - TCP

craniofacial

abnormal cranium morphology ( J:211773 )

IMPC - TCP

growth/size/body

decreased body length ( J:211773 )

IMPC - TCP

hematopoietic system

decreased leukocyte cell number ( J:211773 )

♂

IMPC - TCP

decreased lymphocyte cell number ( J:211773 )

♂

IMPC - TCP

homeostasis/metabolism

increased circulating bilirubin level ( J:211773 )

♂

IMPC - TCP

decreased circulating calcium level ( J:211773 )

IMPC - TCP

decreased circulating phosphate level ( J:211773 )

♀

IMPC - TCP

increased circulating alkaline phosphatase level ( J:211773 )

IMPC - TCP

increased circulating aspartate transaminase level ( J:211773 )

IMPC - TCP

immune system

decreased leukocyte cell number ( J:211773 )

♂

IMPC - TCP

decreased lymphocyte cell number ( J:211773 )

♂

IMPC - TCP

limbs/digits/tail

abnormal humerus morphology ( J:211773 )

IMPC - TCP

abnormal radius morphology ( J:211773 )

IMPC - TCP

abnormal ulna morphology ( J:211773 )

IMPC - TCP

abnormal femur morphology ( J:211773 )

IMPC - TCP

abnormal fibula morphology ( J:211773 )

IMPC - TCP

abnormal tibia morphology ( J:211773 )

IMPC - TCP

short tibia ( J:211773 )

IMPC - TCP

skeleton

abnormal cranium morphology ( J:211773 )

IMPC - TCP

abnormal humerus morphology ( J:211773 )

IMPC - TCP

abnormal radius morphology ( J:211773 )

IMPC - TCP

abnormal ulna morphology ( J:211773 )

IMPC - TCP

abnormal femur morphology ( J:211773 )

IMPC - TCP

abnormal fibula morphology ( J:211773 )

IMPC - TCP

abnormal tibia morphology ( J:211773 )

IMPC - TCP

short tibia ( J:211773 )

IMPC - TCP

abnormal clavicle morphology ( J:211773 )

IMPC - TCP

abnormal scapula morphology ( J:211773 )

IMPC - TCP

abnormal pelvic girdle bone morphology ( J:211773 )

IMPC - TCP

abnormal rib morphology ( J:211773 )

IMPC - TCP

abnormal vertebrae morphology ( J:211773 )

IMPC - TCP

abnormal bone structure ( J:211773 )

♀

IMPC - TCP

decreased bone mineral content ( J:211773 )

IMPC - TCP

decreased bone mineral density ( J:211773 )

IMPC - TCP

abnormal joint morphology ( J:211773 )

IMPC - TCP