Phenotypes for Atmin Cd79a Tg(IghMyc)22Bri MGI:5755462 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Atmin^tm1.1Jhh/Atmin^tm1.1Jhh Cd79a^tm1(cre)Reth/Cd79a⁺ Tg(IghMyc)22Bri/0
Genetic Background	B6.Cg-Cd79a^tm1(Cre)Reth Atmin^tm1.1Jhh Tg(IghMyc)22Bri

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atmin^tm1.1Jhh mutation (2 available); any Atmin mutation (39 available)
Cd79a^tm1(cre)Reth mutation (3 available); any Cd79a mutation (29 available)
Tg(IghMyc)22Bri mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

increased B cell apoptosis ( J:230105 )

• 15-fold

decreased B cell number ( J:230105 )

• 7.5-fold compared with Tg(IghMyc)22Bri mice

decreased immature B cell number ( J:230105 )

• 60-fold compared with Cd79a^tm1(Cre)Reth/Cd79a⁺ or Tg(IghMyc)22Bri mice

neoplasm

decreased lymphoma incidence ( J:230105 )

• compared with Tg(IghMyc)22Bri mice

increased tumor latency ( J:230105 )

• compared with Tg(IghMyc)22Bri mice

• however, the range to tumor types is the same

cellular

increased B cell apoptosis ( J:230105 )

• 15-fold

hematopoietic system

increased B cell apoptosis ( J:230105 )

• 15-fold

decreased B cell number ( J:230105 )

• 7.5-fold compared with Tg(IghMyc)22Bri mice

decreased immature B cell number ( J:230105 )

• 60-fold compared with Cd79a^tm1(Cre)Reth/Cd79a⁺ or Tg(IghMyc)22Bri mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 01/20/2026 MGI 6.24