About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5703655
Allelic
Composition		 Havcr2tm1Vlcg/Havcr2tm1Vlcg
Tg(TcraTcrb)1100Mjb/?
Genetic
Background		 B6.Cg-Havcr2tm1Vlcg Tg(TcraTcrb)1100Mjb
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Havcr2tm1Vlcg mutation (0 available); any Havcr2 mutation (30 available)
Tg(TcraTcrb)1100Mjb mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased T cell number ( J:209885 )
• reduced persistence of CD8alphaloCD11ahi cells
decreased interferon-gamma secretion ( J:209885 )
• IFN-gamma producing cells are reduced at 7 days after infection and pulse with OVA

hematopoietic system
decreased T cell number ( J:209885 )
• reduced persistence of CD8alphaloCD11ahi cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory