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Phenotypes Associated with This Genotype
Genotype
MGI:5603313
Allelic
Composition		 Adamts5tm1Dgen/Adamts5tm1Dgen
Adamts9tm1.1Apte/Adamts9tm1.1Apte
Tg(Prrx1-cre)1Cjt/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adamts5tm1Dgen mutation (1 available); any Adamts5 mutation (56 available)
Adamts9tm1.1Apte mutation (1 available); any Adamts9 mutation (90 available)
Tg(Prrx1-cre)1Cjt mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
syndactyly ( J:213412 )
• 100% incidence of soft tissue syndactyly
• phenotype is more severe than in either allele alone

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory