Phenotypes for Adamts5 Adamts9 Tg(Prrx1-cre)1Cjt MGI:5603313 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Adamts5^tm1Dgen/Adamts5^tm1Dgen Adamts9^tm1.1Apte/Adamts9^tm1.1Apte Tg(Prrx1-cre)1Cjt/0
Genetic Background	involves: 129P2/OlaHsd * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adamts5^tm1Dgen mutation (1 available); any Adamts5 mutation (56 available)
Adamts9^tm1.1Apte mutation (1 available); any Adamts9 mutation (90 available)
Tg(Prrx1-cre)1Cjt mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

syndactyly ( J:213412 )

• 100% incidence of soft tissue syndactyly

• phenotype is more severe than in either allele alone

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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