Phenotypes for Ctnnb1 Lyz2 MGI:5581954 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ctnnb1^tm1Mmt/Ctnnb1⁺ Lyz2^tm1(cre)Ifo/Lyz2⁺
Genetic Background	involves: 129P2/OlaHsd * 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ctnnb1^tm1Mmt mutation (0 available); any Ctnnb1 mutation (49 available)
Lyz2^tm1(cre)Ifo mutation (14 available); any Lyz2 mutation (41 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

skeleton phenotype ( J:178340 )

N	• mice exhibit normal bone formation

abnormal osteoclast differentiation ( J:178340 )

• impaired

increased bone volume ( J:178340 )

decreased bone resorption ( J:178340 )

hematopoietic system

abnormal osteoclast differentiation ( J:178340 )

• impaired

decreased bone marrow cell number ( J:178340 )

cellular

abnormal osteoclast differentiation ( J:178340 )

• impaired

immune system

abnormal osteoclast differentiation ( J:178340 )

• impaired

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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