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Phenotypes Associated with This Genotype
Genotype
MGI:5574306
Allelic
Composition		 Gt(ROSA)26Sortm1.1(Ubc-BCL3)Sbn/Gt(ROSA)26Sor+
Cd79atm1(cre)Reth/Cd79a+
Genetic
Background		 involves: BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd79atm1(cre)Reth mutation (3 available); any Cd79a mutation (26 available)
Gt(ROSA)26Sortm1.1(Ubc-BCL3)Sbn mutation (0 available); any Gt(ROSA)26Sor mutation (1095 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased B cell proliferation ( J:207111 )
• slightly less in LPS-stimulated marginal zone
• however, proliferation of alphaIgM-stimulated follicular B cells is not significantly different from that of wild-type cells
increased follicular B cell number ( J:207111 )
• total and FO II B cells

hematopoietic system
decreased B cell proliferation ( J:207111 )
• slightly less in LPS-stimulated marginal zone
• however, proliferation of alphaIgM-stimulated follicular B cells is not significantly different from that of wild-type cells
increased follicular B cell number ( J:207111 )
• total and FO II B cells

cellular
decreased B cell proliferation ( J:207111 )
• slightly less in LPS-stimulated marginal zone
• however, proliferation of alphaIgM-stimulated follicular B cells is not significantly different from that of wild-type cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory