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Phenotypes Associated with This Genotype
Genotype
MGI:5556244
Allelic
Composition		 Krastm4Tyj/Kras+
Tg(Krt1-15-cre/PGR*)22Cot/0
Genetic
Background		 involves: 129S4/SvJae * C57BL/6 * C57BL/6J * SJL/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Krastm4Tyj mutation (9 available); any Kras mutation (84 available)
Tg(Krt1-15-cre/PGR*)22Cot mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased papilloma incidence ( J:203922 )
• mice develop benign papillomas without progressing to malignancy following topical application of RU486 to the back of skin at 3 weeks of age for 5 days

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/22/2024
MGI 6.24 		The Jackson Laboratory