Phenotypes for Slc12a2 Tbx1 Tg(Pax2-cre)1Akg MGI:5538349 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Slc12a2^tm1.1Jheb/Slc12a2^tm1.1Jheb Tbx1^tm6(cre)Bld/Tbx1⁺ Tg(Pax2-cre)1Akg/0
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc12a2^tm1.1Jheb mutation (0 available); any Slc12a2 mutation (58 available)
Tbx1^tm6(cre)Bld mutation (1 available); any Tbx1 mutation (36 available)
Tg(Pax2-cre)1Akg mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

hyperactivity ( J:201156 )

circling ( J:201156 )

hearing/vestibular/ear

abnormal inner ear morphology ( J:201156 )

• collapse of the membranes of the vestibular compartments

collapsed Reissner membrane ( J:201156 )

abnormal crista ampullaris morphology ( J:201156 )

• cristae degeneration

utricular degeneration ( J:201156 )

vestibular saccular degeneration ( J:201156 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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