Phenotypes for Gt(ROSA)26Sor Lhx6 Tg(Nkx2-1-cre)1Wdr MGI:5491493 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Gt(ROSA)26Sor^tm1(EYFP)Cos/Gt(ROSA)26Sor⁺ Lhx6^tm2Vpa/Lhx6^tm2Vpa Tg(Nkx2-1-cre)1Wdr/0
Genetic Background	involves: 129P2/OlaHsd * 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor^tm1(EYFP)Cos mutation (24 available); any Gt(ROSA)26Sor mutation (1062 available)
Lhx6^tm2Vpa mutation (0 available); any Lhx6 mutation (29 available)
Tg(Nkx2-1-cre)1Wdr mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal brain interneuron morphology ( J:196342 )

• mice exhibit impaired somatostatin+ cortical interneuron differentiation compared with control mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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