Tg(Nkx2-1-cre)1Wdr
Transgene Detail

Summary

• Symbol: Tg(Nkx2-1-cre)1Wdr
• Name: transgene insertion 1, William D Richardson
• MGI ID: MGI:3761164
• Synonyms: Nkx2.1^Cre, Nkx2.1-Cre, Nkx2.1:Cre, Nkx2.1iCre
• Transgene: Tg(Nkx2-1-cre)1Wdr Location: unknown
• Alliance: Tg(Nkx2-1-cre)1Wdr page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Nkx2-1-cre)1Wdr expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Nkx2-1

• Mutation details: A P1 artificial chromosome was created that contained a condon-improved Cre recombinase with a nuclear localization signal fused to the initiation codon. Expression recapitulates endogenous expression in the medial ganglionic eminence, septum, anterior entopeduncular area, preoptic area and other more posterior ventral forebrain regions. (J:105334)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Nkx2-1 (species not specified) Summary of all recombinase alleles driven by Nkx2-1. Comparative matrix view of recombinase activities

Expression

In Mice Carrying this Mutation:

2 assay results 2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:105334 Kessaris N, et al., Competing waves of oligodendrocytes in the forebrain and postnatal elimination of an embryonic lineage. Nat Neurosci. 2006 Feb;9(2):173-9
• All: 31 reference(s)