Phenotypes Associated with This Genotype

Genotype
MGI:5478601

• Allelic Composition: Cdcp1^tm1.2Moas/Cdcp1^tm1.2Moas; Tg(MMTV-PyVT)634Mul/0
• Genetic Background: involves: 129 * C57BL/6 * FVB/N * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

decreased tumor-free survival time ( J:194368 )

• mice are euthanized at 12 weeks due to numerous large tumors

neoplasm

increased tumor growth/size ( J:194368 )

• accelerated tumorigenesis compared with Tg(MMTV-PyVT)634Mul mice

increased tumor incidence ( J:194368 )

• at 12 weeks mice exhibit a 2.6-fold increase in the number of tumors per mouse with an average of 5.7-fold increase in total tumor burden compared with Tg(MMTV-PyVT)634Mul mice

• with lung metastases