Phenotypes for Map3k7 Tg(Tek-cre)12Flv Tnfrsf1a MGI:5464102 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Map3k7^tm1Aki/Map3k7^tm1Aki Tnfrsf1a^tm1Mak/Tnfrsf1a^tm1Mak Tg(Tek-cre)12Flv/0
Genetic Background	involves: 129P2/OlaHsd * 129S2/SvPas * C3H * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Map3k7^tm1Aki mutation (0 available); any Map3k7 mutation (52 available)
Tg(Tek-cre)12Flv mutation (1 available)
Tnfrsf1a^tm1Mak mutation (2 available); any Tnfrsf1a mutation (51 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:191285 )

• mice die by E13.5

cardiovascular system

cardiovascular system phenotype ( J:191285 )

N	• blood vessels do not exhibit regression and exhibit normal vessel length and branching

dilated vasculature ( J:191285 )

cellular

cellular phenotype ( J:191285 )

N	• embryonic endothelial cell apoptosis is rescued

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 01/20/2026 MGI 6.24