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Phenotypes Associated with This Genotype
Genotype
MGI:5461331
Allelic
Composition		 Bcl6tm1.1Mtto/Bcl6tm1.1Mtto
Cd79atm1(cre)Reth/Cd79a+
Tg(Cd4-cre)1Cwi/0
Genetic
Background		 involves: BALB/c * C57BL/6 * C57BL/6JJcl * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bcl6tm1.1Mtto mutation (1 available); any Bcl6 mutation (60 available)
Cd79atm1(cre)Reth mutation (3 available); any Cd79a mutation (29 available)
Tg(Cd4-cre)1Cwi mutation (12 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:190943 )
N
• mice immunized with NP-CG exhibit normal development of memory B cells
decreased germinal center B cell number ( J:190943 )
• in mice immunized with NP-CG

hematopoietic system
decreased germinal center B cell number ( J:190943 )
• in mice immunized with NP-CG

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory