Phenotypes Associated with This Genotype

Genotype
MGI:5437516

• Allelic Composition: Gt(ROSA)26Sor^{tm1(CAG-Bmi1,-EGFP)Nki}/Gt(ROSA)26Sor⁺; Rb1^tm2Brn/Rb1^tm2Brn; Tg(Gfap-cre)2Brn/0
• Genetic Background: either: (involves: 129 * 129P2/OlaHsd * FVB/N) or (involves: 129 * 129P2/OlaHsd * C57BL/6 * FVB/N)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:187257 )

neoplasm

neoplasm ( J:187257 )

N • mice do not develop medulloblastoma

increased pituitary gland tumor incidence ( J:187257 )

endocrine/exocrine glands

increased pituitary gland tumor incidence ( J:187257 )

nervous system

increased pituitary gland tumor incidence ( J:187257 )