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Phenotypes Associated with This Genotype
Genotype
MGI:5432232
Allelic
Composition
Amhr2tm3(cre)Bhr/Amhr2+
Ctnnb1tm1Mmt/Ctnnb1+
Ptentm1Hwu/Ptentm1Hwu
Genetic
Background
involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Amhr2tm3(cre)Bhr mutation (1 available); any Amhr2 mutation (20 available)
Ctnnb1tm1Mmt mutation (0 available); any Ctnnb1 mutation (32 available)
Ptentm1Hwu mutation (3 available); any Pten mutation (53 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
• female mutants develop granulosa cell tumors by 3 weeks of age
• male mutants develop testicular granulosa cell tumors by 5 weeks of age

reproductive system
• female mutants develop granulosa cell tumors by 3 weeks of age
• male mutants develop testicular granulosa cell tumors by 5 weeks of age

neoplasm
• female mutants develop granulosa cell tumors by 3 weeks of age
• male mutants develop testicular granulosa cell tumors by 5 weeks of age


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/08/2017
MGI 6.10
The Jackson Laboratory