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Phenotypes Associated with This Genotype
Genotype
MGI:5432223
Allelic
Composition
Ctnnb1tm1Mmt/Ctnnb1+
Tg(CYP19A1-cre)1Jri/0
Genetic
Background
involves: 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ctnnb1tm1Mmt mutation (0 available); any Ctnnb1 mutation (27 available)
Tg(CYP19A1-cre)1Jri mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
• ovaries exhibit visible precancerous lesions between 4 and 6 weeks of age and develop granulosa cell tumors

reproductive system
• ovaries exhibit visible precancerous lesions between 4 and 6 weeks of age and develop granulosa cell tumors

mortality/aging
• mutants die within 6-8 months of age

neoplasm
• ovaries exhibit visible precancerous lesions between 4 and 6 weeks of age and develop granulosa cell tumors

Mouse Models of Human Disease
OMIM ID Ref(s)
Ovarian Cancer 167000 J:186144


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory