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Phenotypes Associated with This Genotype
Genotype
MGI:5430385
Allelic
Composition		 Krastm4Tyj/Krastm4Tyj
Ugdhtm1.1Xzh/Ugdhtm1.1Xzh
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Genetic
Background		 involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * CBA/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2az2Tg(Wnt1-cre)11Rth mutation (2 available); any H2az2 mutation (25 available)
Krastm4Tyj mutation (11 available); any Kras mutation (69 available)
Ugdhtm1.1Xzh mutation (1 available); any Ugdh mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
abnormal lacrimal gland development ( J:185652 )
• disruption of lacrimal gland budding

vision/eye
abnormal lacrimal gland development ( J:185652 )
• disruption of lacrimal gland budding

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory