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Phenotypes Associated with This Genotype
Genotype
MGI:5429557
Allelic
Composition
Celsr2tm1Lex/Celsr2tm1Lex
Genetic
Background
involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Celsr2tm1Lex mutation (0 available); any Celsr2 mutation (59 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• normal behavior

growth/size/body
N
• situs inversus was not observed

nervous system
• 12 of 13 mice exhibit mild to moderate dilation of the lateral ventricle with mild compression of the surrounding neuropil
• 12 of 13 mice exhibit mild to moderate dilation of the third ventricle with mild compression of the surrounding neuropil

reproductive system
N
• normal fertility

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
hydrocephalus DOID:10908 OMIM:123155
OMIM:236600
OMIM:236635
OMIM:307000
OMIM:615219
J:185566


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory