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Phenotypes Associated with This Genotype
Genotype
MGI:5427983
Allelic
Composition		 Dhx36tm1.2Pmt/Dhx36tm1.2Pmt
Tg(Mx1-cre)1Cgn/0
Genetic
Background		 involves: 129P2/Ola * 129S4/SvJaeSor * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dhx36tm1.2Pmt mutation (1 available); any Dhx36 mutation (55 available)
Tg(Mx1-cre)1Cgn mutation (10 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal erythropoiesis ( J:185179 )
• in competitive repopulation assays, mice transplanted with bone marrow from pIpC-treated mice exhibit impaired erythropoiesis compared with mice transplanted with control bone marrow
abnormal leukopoiesis ( J:185179 )
• in competitive repopulation assays, mice transplanted with bone marrow from pIpC-treated mice exhibit impaired leukopoiesis compared with mice transplanted with control bone marrow

immune system
abnormal leukopoiesis ( J:185179 )
• in competitive repopulation assays, mice transplanted with bone marrow from pIpC-treated mice exhibit impaired leukopoiesis compared with mice transplanted with control bone marrow

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory