Phenotypes for Bmp2 Bmp4 Bmp7 H2az2 MGI:5312874 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Bmp2^tm1Jfm/Bmp2⁺ Bmp4^tm1Jfm/Bmp4^tm1Jfm Bmp7^tm1Jfm/Bmp7^tm1Jfm H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺
Genetic Background	involves: 129S4/SvJaeSor * C57BL/6J * CBA/J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bmp2^tm1Jfm mutation (1 available); any Bmp2 mutation (25 available)
Bmp4^tm1Jfm mutation (1 available); any Bmp4 mutation (23 available)
Bmp7^tm1Jfm mutation (0 available); any Bmp7 mutation (37 available)
H2az2^{Tg(Wnt1-cre)11Rth} mutation (2 available); any H2az2 mutation (25 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

craniofacial

small interparietal bone ( J:181229 )

small temporal bone squamous part ( J:181229 )

• decreased size

small nasal bone ( J:181229 )

small zygomatic bone ( J:181229 )

cleft palate ( J:181229 )

hearing/vestibular/ear

abnormal tympanic ring morphology ( J:181229 )

• missing pieces

digestive/alimentary system

cleft palate ( J:181229 )

skeleton

small interparietal bone ( J:181229 )

small temporal bone squamous part ( J:181229 )

• decreased size

small nasal bone ( J:181229 )

small zygomatic bone ( J:181229 )

growth/size/body

small nasal bone ( J:181229 )

small zygomatic bone ( J:181229 )

cleft palate ( J:181229 )

respiratory system

small nasal bone ( J:181229 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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