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Phenotypes Associated with This Genotype
Genotype
MGI:5297713
Allelic
Composition		 Msx1tm1Bero/Msx1tm2.1(cre/ERT2)Bero
Msx2tm1Yvla/Msx2tm1Yvla
Genetic
Background		 involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * NMRI
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Msx1tm1Bero mutation (1 available); any Msx1 mutation (18 available)
Msx1tm2.1(cre/ERT2)Bero mutation (2 available); any Msx1 mutation (18 available)
Msx2tm1Yvla mutation (0 available); any Msx2 mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal carotid artery morphology ( J:173525 )
• increased carotid artery vessel diameter is observed
vascular smooth muscle hypoplasia ( J:173525 )
• a reduction in vascular smooth muscle cell (VSMC) coverage (depletion of mural cells) is observed

muscle
vascular smooth muscle hypoplasia ( J:173525 )
• a reduction in vascular smooth muscle cell (VSMC) coverage (depletion of mural cells) is observed

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory