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Phenotypes Associated with This Genotype
Genotype
MGI:5294364
Allelic
Composition		 Qpcttm1.2Tbay/Qpcttm1.2Tbay
Trib2Tg(Thy1-Trh/APP*)2.1Ingm/Trib2Tg(Thy1-Trh/APP*)2.1Ingm
Genetic
Background		 involves: 129S2/SvPas * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Qpcttm1.2Tbay mutation (0 available); any Qpct mutation (8 available)
Trib2Tg(Thy1-Trh/APP*)2.1Ingm mutation (0 available); any Trib2 mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
amyloid beta deposits ( J:176575 )
• the pyroglutamate amyloid beta load is reduced compared to transgenic mice wild-type for Qpct

homeostasis/metabolism
amyloid beta deposits ( J:176575 )
• the pyroglutamate amyloid beta load is reduced compared to transgenic mice wild-type for Qpct

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory