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Phenotypes Associated with This Genotype
Genotype
MGI:5292731
Allelic
Composition		 Faslpr/Fas+
Tg(TcraTcrb)1100Mjb/?
Genetic
Background		 involves: C57BL/6 * MRL/Mp
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Faslpr mutation (39 available); any Fas mutation (83 available)
Tg(TcraTcrb)1100Mjb mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:72817 )
N
• after administration of OVA peptide 257-264 has no affect on mortality

liver/biliary system
liver/biliary system phenotype ( J:72817 )
N
• no morphological abnormalities or increased apoptosis after administration of OVA peptide 257-264
liver inflammation ( J:72817 )
• extensive infiltration of Valpha2+ CD8+ lymphocytes after administration of OVA peptide 257-264

immune system
liver inflammation ( J:72817 )
• extensive infiltration of Valpha2+ CD8+ lymphocytes after administration of OVA peptide 257-264

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory