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Phenotypes Associated with This Genotype
Genotype
MGI:5285556
Allelic
Composition		 Foxj1tm1.1Ctk/Foxj1tm1.2Ctk
Tg(FOXJ1-EGFP)85Leo/0
Tg(Nes-cre)1Kln/0
Genetic
Background		 involves: C3H * C57BL/6 * C57BL/6J * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxj1tm1.1Ctk mutation (0 available); any Foxj1 mutation (20 available)
Foxj1tm1.2Ctk mutation (0 available); any Foxj1 mutation (20 available)
Tg(FOXJ1-EGFP)85Leo mutation (1 available)
Tg(Nes-cre)1Kln mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal neuron differentiation ( J:174694 )
• postnatal radial glial progenitors fail to organize into clusters unlike in wild-type mice
• neural stem cells fail to form ependymal niches unlike in wild-type mice
• however, RC2+ radial glial cells transition into neural stem cells

cellular
abnormal neuron differentiation ( J:174694 )
• postnatal radial glial progenitors fail to organize into clusters unlike in wild-type mice
• neural stem cells fail to form ependymal niches unlike in wild-type mice
• however, RC2+ radial glial cells transition into neural stem cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory