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Phenotypes Associated with This Genotype
Genotype
MGI:5285375
Allelic
Composition		 Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Sox11tm1.1Vlf/Sox11tm1.1Vlf
Sox4tm1Vlf/Sox4tm1Vlf
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Genetic
Background		 involves: 129 * C57BL/6 * C57BL/6J * CBA/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1Sor mutation (10 available); any Gt(ROSA)26Sor mutation (1062 available)
H2az2Tg(Wnt1-cre)11Rth mutation (2 available); any H2az2 mutation (25 available)
Sox11tm1.1Vlf mutation (0 available); any Sox11 mutation (14 available)
Sox4tm1Vlf mutation (1 available); any Sox4 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
abnormal pharyngeal arch development ( J:175338 )
• massive cell death in the branchial arches without a decrease in cell proliferation

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory